CORRELATION BETWEEN PROMOTER HYPERMETHYLATION AND EXPRESSION PROFILES OF P15INK4B AND P16INK4A GENES ON DEVELOPMENT OF PTERYGIUM DISEASE

Correlation between Promoter Hypermethylation and Expression Profiles of P15INK4b and P16INK4a Genes on Development of Pterygium Disease

Background: It is not thoroughly clear that what is the exact etiology of pterygium.Recently, it has been illustrated that pterygium is a benign and destructive condition.The aim of this study was to examine the correlation between promoter hypermethylation of P15INK4band P16INK4a genes on progress of pterygium.Materials and methods: swisse high st

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Case report: Development of central precocious puberty in a girl with late-diagnosed simple virilizing congenital adrenal hyperplasia complicated with Williams syndrome

Congenital adrenal hyperplasia (CAH) and Williams Syndrome (WS; MIM # 194050) are distinct genetic conditions characterized by unique clinical features.21-Hydroxylase deficiency (21-OHD; MIM #201910), the most common form of CAH, arises from mutations in the CYP21A2 gene, resulting in virilization of the external genitalia in affected females, earl

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